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Description
The Accuris™ MR9620 SmartReader™ MultiMode Plate Reader is an all-in-one microplate reader for absorbance, fluorescence and luminescence, built to meet the growing needs of advanced life science laboratories. It reads standard 96-well plates as well as 6-, 12-, 24-, 48- and 384-well plates, and is programmed and operated entirely from its large 10-inch color touch screen — no external computer or software is required.
UV-Visible absorbance: an advanced monochromator and long-life, broad-spectrum xenon flash lamp deliver any wavelength from 200 to 1000 nm in 1 nm steps, reading a full 96-well plate in under 15 seconds. Kinetic assays display a curve for every well in real time, and the optional SmartDrop™ plate (MR9610-SDP) measures up to 16 nucleic acid or protein droplets.
Fluorescence: three filter modules covering the most common excitation/emission pairs are included, and additional modules are available. The modules combine dichroic mirrors with narrow band-pass filters for high light transmission and sensitivity, are easily exchanged, and are barcoded so wavelength data load automatically. Automatic dynamic range selection adjusts PMT gain to capture and normalize signal intensity.
Luminescence: an advanced PMT handles both flash and glow assays, enhancing weak signals while preventing saturation of strong ones. Up to two sample injectors (available separately) can be installed and work with 96- and 384-well plates.
A built-in shaker offers linear, orbital and double-orbital modes, and top-heating incubation from ambient +4°C to 45°C creates a gradient that prevents condensation on lidded plates. At start-up the reader runs a self-diagnostic and automatic calibration of the whole system. Data export as .XLS or .CSV via the included USB flash drive or FTP server, or through the optional SmartReader™ PC Software (research version MR9620-PC, or FDA 21 CFR Part 11 compliant version MR9620-CFR).
Applications:
- ELISA and colorimetric assays (Bradford, Lowry and more)
- Enzyme kinetics and spectral scanning
- DNA and RNA analysis
- Fluorescence intensity assays
- Flash and glow luminescence assays
Features:
- Absorbance, fluorescence and luminescence in one instrument
- Intuitive 10-inch color touch screen; stand-alone operation
- Monochromator absorbance, 200–1000 nm in 1 nm steps
- Barcoded, interchangeable fluorescence filter modules (3 included)
- PMT luminescence detection for flash and glow assays
- Accepts 6- to 384-well plates
- Linear, orbital and double-orbital shaking; top-heated incubation to 45°C
- Optional PC software, including FDA 21 CFR Part 11 version
Technical Specifications:
| Model | Accuris™ SmartReader™ MultiMode MR9620 |
| Measurement Technologies | Absorbance, fluorescence, luminescence |
| Plate Formats | 6- to 384-well plates |
| Shaking | Linear (4.7, 7.0, 13.5 Hz), orbital and double orbital (240–1,200 rpm) |
| Incubation Range | Ambient +4°C to 45°C (top heating) |
| Display | 10-inch touch screen |
| Communication Ports | 2 USB-A, 1 USB-B, 1 Ethernet, RS232 |
| Power Input | 100–240V AC, 50/60 Hz |
| Dimensions (W x D x H) | 42.0 x 55.0 x 38.6 cm (16.5 x 21.7 x 15.2 in) |
| Weight | 33 kg (72.8 lb) |
| Absorbance | |
| Light Source | High-energy xenon flash lamp |
| Detector | Photodiode |
| Wavelength Range | 200–1000 nm, 1 nm steps |
| Wavelength Accuracy / Repeatability | 2 nm / 0.2 nm |
| Bandwidth (FWHM) | 2.5 nm |
| Absorbance Range | 0.0–4.0 OD |
| Resolution | 0.0001 OD |
| Accuracy (96-well, precision mode) | ±(1.0% + 0.003 Abs) at 0.0–2.0 Abs; ±2.0% at 2.0–3.0 Abs |
| Repeatability | CV <1.0% or SD <0.003 (fast); CV <0.5% or SD <0.003 (accurate), 0.0–3.0 Abs |
| Stray Light | 0.1% at 220 nm |
| Linearity | R² >0.999 at 0.0–3.0 Abs |
| Measurement Speed | <15 seconds per 96-well plate |
| Fluorescence | |
| Reading Mode | Top reading |
| Excitation Light Source | High-energy xenon flash lamp |
| Detector | Photomultiplier tube (PMT) |
| Detection Limit | ≤1 pM |
| Wavelength Range | EX 200–1000 nm; EM 270–850 nm |
| Included Filter Modules (EX/EM) | 485/530 nm; 523/564 nm; 624/692 nm |
| Linear Dynamic Range | 6 logs |
| Luminescence | |
| Detector | Photomultiplier tube (PMT) |
| Detection Limit | 15 amol/well |
| Linear Dynamic Range | 6 logs |
| Injectors | Up to 2 optional automatic injection modules (MR9620-AIM1 / -AIM2) |
